Sertoli Cell Biology

Sertoli Cell Biology, Second Edition summarizes the progress since the last edition and emphasizes the new information available on Sertoli/germ cell interactions. This information is especially timely since the progress in the past few years has been exceptional and it relates to control of sperm production in vivo and in vitro.

Fully revisedWritten by experts in the fieldSummarizes 10 years of researchContains clear explanations and summaries  Provides a summary of references over the last 10 years

Preface
Sertoli cell anatomy and cytoskeleton
Fetal Sertoli cells
Early postnatal interactions between Sertoli and germ cells
Stem cell Niche
Role of DMRT1
Hormonal regulation of spermatogenesis through Sertoli cells- Testosterone
Activins and inhibins
Initiation of spermatogenesis and the cycle of the seminiferous epithelium
Retinoic acid metabolism and the cycle of the seminiferous epithelium
Sertoli cell specific transcription and the Sertoli cell cycle
Micro-RNA and spermatogenesis
Large noncoding RNAs (lncRNAs) and lncRNA-mediated epigenetic regulation
Biochemistry of Sertoli-Germ cell junctions, spermiation and movement of germ cells across the barrier
Immunology of the Testis
Diversity and similarities in Sertoli cells from different species
Human Sertoli cells and the SCO syndrome
Gene Knockouts that affect Sertoli cell function