Craniopharyngiomas: Comprehensive Diagnosis, Treatment and Outcome

Craniopharyngiomas: A Comprehensive Guide to Diagnosis, Treatment and Outcome is a comprehensive guide to the science, diagnosis and treatment of craniopharyngiomas, rare brain tumors that grow near the pituitary gland. Even though these tumors are generally benign, due to the location, prognosis was often bleak. This reference provides a resource for specialists requiring a comprehensive overview of this rare form of tumor, outlining new diagnostic, imaging and surgical techniques, including endoscopic endonasal cranial base surgery, which enable successful neurosurgical intervention. With a better prognosis, patients require multidisciplinary management from neurology, otolaryngology, radiation oncology, endocrinology, and neuropathology.

The only comprehensive guide to the science, diagnosis and treatment of craniopharyngiomasIncludes multidisciplinary management from neurology, otolaryngology, radiation oncology, endocrinology, and neuropathologyDetailed coverage of the impacts of new diagnostic, imaging and neurosurgical techniques including endoscopic endonasal cranial base surgery

Section I: Introduction 1. Natural History 2. Anatomical Considerations 3. Imaging of Craniopharyngiomas and Radiologic Differential Diagnosis 4. Embryology, Pathology and Molecular Aspects

Section II: Medical Evaluation 5. Craniopharyngioma: Neuroendocrine Evaluation and Management 6. Neuro-Ophthalmic Manifestations of Craniopharyngiomas

Section III: Surgical Approaches 7. Surgical Approaches Introduction and Outcomes 8. Endoscopic Resection of Craniopharyngiomas  9. The Microscopic Transsphenoidal Approach for Craniopharyngiomas 10. Pterional Approach for the Resection of Craniopharyngioma 11. The Frontolateral Approach to Adult Craniopharyngiomas 12. Supraorbital Eyebrow Approach for Craniopharyngiomas 13. Transcortical-Transventricular Removal of Craniopharyngioma 14. Petrosal Approach for Retrochiasmatic Craniopharyngiomas 15. Endoscopic Transventricular Approach to Craniopharyngiomas 16. Ommaya Reservoir for Cystic Craniopharyngiomas 17. Endonasal Resection of Craniopharyngiomas: Postoperative Management 18. Complications of Surgical Management

Section IV: Radiotherapy 19. Radiotherapy and Radiosurgery for Craniopharyngiomas 20. Stereotactic Radiosurgery as Part of Multimodality Craniopharyngioma Management 21. Linear Accelerator Based Fractionated Radiotherapy 22. The Role of Proton Therapy in Treatment of Craniopharyngioma 23. Craniopharyngioma: Radiation Toxicities

Section V: Intracavitary Therapy 24. Radioisotopes: 32P, 90Y, and 186Re 25. Intracavitary Chemotherapy

Section VI: Management of Recurrence 26. Management of Recurrence of Craniopharyngiomas

Section VII: Special Considerations 27. Craniopharyngioma – Pediatric Management 28. Surgery of Craniopharyngiomas in Children 29. Pediatric Radiation 30. Management of Giant Craniopharyngiomas 31. Ectopic Occurrence of Craniopharyngiomas 32. Malignant transformation of Craniopharyngioma

Section VIII: Controversies 33. Incomplete Resection or Craniopharyngiomas 34. Complete Resection of Craniopharyngiomas 35. Extended Endoscopic vs. Open Transcranial Approaches 36. Endoscopic Resection