Basic and Applied Bone Biology

This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models.

Presents an in-depth overview of skeletal biology from the molecular to the organ levelOffers "refresher" level content for clinicians or researchers outside their areas of expertiseBoasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology

Basic Bone Biology and Physiology

Chapter 1: Bone morphology and organization

Chapter 2: Bone cells

Chapter 3: Local regulation of bone cell function

Chapter 4: Bone modeling and remodeling

Assessment of Bone Structure and Function

Chapter 5: Skeletal imaging

Chapter 6: Skeletal hard tissue biomechanics

Chapter 7: Techniques in histomorphometry

Chapter 8: Skeletal genetics

Skeletal adaptation

Chapter 9: Mechanical adaptation

Chapter 10: Fracture healing

Chapter 11: Craniofacial biology, orthodontics, and implants

Hormonal and Metabolic Effects on Bone

Chapter 12: Skeletal growth and development

Chapter 13: Calcium and phosphate: Hormonal regulation and metabolism

Chapter 14: Nutrition

Chapter 15: Hormonal effects on bone cells

Skeletal disease and treatment

Chapter 16: Metabolic bone diseases

Chapter 17: Pharmaceutical treatments of osteoporosis