Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy.

With chapters authored by experts in each topic, this book advances the understanding of:

How the brain carries out important tasks via networksHow these networks interact in normal brain functionMajor mechanisms that control network functionThe interaction of the normal networks to produce more complex behaviorsHow brain disorders can result from abnormal interactionsHow therapy of disorders can be advanced through this network approach

This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders.

Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevantChapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disordersReflects predominant disciplinary shift from an anatomical to a functional perspective of the brainEdited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

1. Introduction to Neuronal Networks of the Brain
2. Network Computer Modeling
3. Functional Magnetic Resonance Imaging in Epilepsy:  Methods and Applications Using Awake Animals
4. Network Experimental Approaches:  Inactivation, Microinjection, Neuronal Stimulation, and Recording
5. Network Experimental Approaches – ex vivo and ex vivo Networks
6. Network Imaging and Neuronal Firing
7. Network Control Mechanisms - Neuroactive Substances and Cellular Inputs
8. Network Control Mechanisms – Volume Transmission
9. Bursting in the Brain - From Cells to Networks
10. Network Control Mechanisms – Cellular Milieu
11. Neuronal Network Mechanisms - Sex and Development
12. Astrocytic Regulation of Synapses, Neuronal Networks and Behavior
13. The Fear Memory Network
14. Orchestration of the Circadian Clock Network by the Suprachiasmatic Nucleus
15. mTOR Signaling in Cortical Network Development
16. Network Control Mechanisms - Synaptogenesis and Epilepsy Development
17. The Brain and Spinal Cord Networks Controlling Locomotion
18. The Brainstem Respiratory Network
19. Visual Network
20. Auditory Neuronal Networks and Chronic Tinnitus
21. Consciousness and Subcortical Arousal Systems
22. Networks of Normal and Disordered Sleep
23. Networks for the Modulation of Acute and Chronic Pain
24. Networks in Mood and Anxiety Disorders
25. Neuronal Networks and Therapeutics in Neurodegenerative Disorders
26. Neuronal Networks in Epilepsy:  Comparative Audiogenic Seizure Networks
27. Physiological and Pathophysiological Expansion of Neuronal Networks
28. Neuronal Network Plasticity and Network Interactions are Critically Dependent on Conditional Multireceptive (CMR) Brain Regions
29. Neuronal Network Interactions in the Startle Reflex, Learning Mechanisms, and CNS Disorders, Including Sudden Unexpected Death in Epilepsy
30. Emergent Properties of Neuronal Networks
31. Neuronal Network Involvement in Stimulation Therapies for CNS Disorders
32. Neuronal Network Effects of Drug Therapies for CNS Disorders
33. Future Trends in Neuronal Networks - Selective and Combined Targeting of Network Hubs