Advances in the Neurochemistry and Neuropharmacology of Tourette Syndrome

This volume of International Review of Neurobiology brings together cutting-edge research on advances in the neurochemistry and neuropharmacology of Tourette syndrome. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and includes important topics regards tics, neurotransmitters, pharmacology and emerging treatments.

1. An Introduction to the Clinical Phenomenology of Tourette Syndrome

Davide Martino, Namrata Madhusudan, Panagiotis Zis and Andrea E. Cavanna

2. Functional Neuroanatomy of Tics

Irene Neuner, Frank Schneider and N. Jon Shah

3. Functional Imaging of Dopaminergic Neurotransmission in Tourette Syndrome

Bàrbara Segura and Antonio P. Strafella

4. Non-dopaminergic neurotransmission in the pathophysiology of Tourette syndrome

Patrick T. Udvardi, Ester Nespoli, Francesca Rizzo, Bastian Hengerer and Andrea G. Ludolph

5. Reinforcement Learning and Tourette Syndrome

Stefano Palminteri and Mathias Pessiglione

6. Genetic Susceptibility and Neurotransmitters in Tourette Syndrome

Peristera Paschou, Thomas V. Fernandez, Frank Sharp, Gary A. Heiman and Pieter J. Hoekstra

7. Pharmacological Animal Models of Tic Disorders

Kevin W McCairn and Masaki Isoda

8. Animal Models Recapitulating the Multifactorial Origin of Tourette Syndrome

Simone Macrì, Martina Proietti Onori, Veit Roessner and Giovanni Laviola

9. Neuroendocrine Aspects of Tourette Syndrome

Davide Martino, Antonella Macerollo and James F Leckman

10. Clinical Pharmacology of Dopamine-Modulating Agents in Tourette`s Syndrome

Sabine Mogwitz, Judith Buse, Stefan Ehrlich and Veit Roessner

11. Clinical Pharmacology of Non-Dopaminergic Drugs in Tourette Syndrome

Andreas Hartmann

12. Antiepileptic Drugs and Tourette Syndrome

Andrea E. Cavanna and Andrea Nani

13. Clinical Pharmacology of Co-Morbid Obsessive-Compulsive Disorder in Tourette Syndrome

Valeria Neri and Francesco Cardona

14. Clinical Pharmacology of Comorbid Attention Deficit Hyperactivity Disorder in Tourette Syndrome

Renata Rizzo and Mariangela Gulisano

15. Emerging Treatment Strategies in Tourette syndrome: What’s in the Pipeline?

C. Termine, C. Selvini, G. Rossi and U. Balottin

16. Tics and Other Stereotyped Movements as Side Effects of Pharmacological Treatment Marcos Madruga-Garrido and Pablo Mir