Rosenbergs Molecular and Genetic Basis of Neurological and Psychiatric Disease

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format.

Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases.

Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric diseaseDetailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brainDetailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients with biochemical abnormalities or gene mutations

Section I.  GENERAL CONCEPTS AND TOOLS

Section II.  NEUROLOGIC DISEASES

                   NEUROMETABOLIC DISORDERS

                   Mitochondrial Disorders

                   Lysosomal Disorders

                   Metal Metabolism Disorders

                   Vitamin Disorders

                   Lipid Metabolism Disorders

                   Other Metabolic Disorders

                   DEGENERATIVE DISORDERS

                   MOVEMENT DISORDERS

                   NEURO-ONCOLOGY

                   NEUROCUTANEOUS DISORDERS

                   EPILEPSY

                   WHITE MATTER DISEASES

                   NEUROPATHIES AND NEURONOPATHIES

                   MUSCLE AND NEUROMUSCULAR JUNCTION DISORDERS

                   STROKE

Section III.  PSYCHIATRIC DISEASE

Section IV.  A NEUROLOGIC AND PSYCHIATRIC GENE MAP