Cellular Adhesion in Development and Disease

Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more.

1. How Adhesion forms the early Mammalian Embryo
Melanie D. White and Nicolas Plachta
2. Regulation of Cell Adhesion and Cell Sorting at Embryonic Boundaries
François Fagotto
3. Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional Contractility
Rashmi Priya and Alpha S. Yap
4. Integration of Cell-Cell Adhesion and Contractile Actomyosin Activity during Morphogenesis
Katja Röper
5. Nuclear Signaling from Cadherin Adhesion Complexes
Pierre D. McCrea, Meghan T. Maher and Cara J. Gottardi
6. Nectins and Nectin-Like Molecules in Development and Disease
Kenji Mandai, Yoshiyuki Rikitake, Masahiro Mori and Yoshimi Takai
7. Anchors and Signals: The Diverse Roles of Integrins in Development
Aidan P. Maartens and Nicholas H. Brown
8. Epithelial-Mesenchymal Transitions: From Cell Plasticity to Concept Elasticity
Pierre Savagner
9. Embryonic Cell-Cell Adhesion: A Key Player in Collective Neural Crest Migration
Elias H Barriga and Roberto Mayor
10. VE-Cadherin in Vascular Development: A Coordinator of Cell Signaling and Tissue Morphogenesis
Anne Karine Lagendijk and Benjamin M. Hogan
11. Adhesion in Mammary Development: Novel Roles for E-Cadherin in Individual and Collective Cell Migration
Eliah R. Shamir and Andrew J. Ewald
12. Cell Adhesion in Epidermal Development and Barrier Formation
Kaelyn D. Sumigray and Terry Lechler
13. Cadherin-Based Trans-Synaptic Networks in Establishing and Modifying Neural Connectivity
Lauren G. Friedman, Deanna L. Benson and George W. Huntley
14. Cell-Cell Interactions Driving Kidney Morphogenesis
Alexander N. Combes, Jamie Davies and Melissa Little