bHLH Transcription Factors in Development and Disease

This new volume of Current Topics in Developmental Biology provides a comprehensive set of reviews on bHLH transcription factors.  bHLH factors are vastly recognized for their diverse roles in developmental processes and their dysfunction underlies various human pathologies.  Each chapter is authoritatively written by a leading expert in the field and discusses every possible aspect of this huge and diverse field.

Covers the area of basic helix-loop-helix (bHLH) transcription factors in development and diseaseInternational board of authors Provides a comprehensive set of reviews on our current understanding on the function of bHLH factors in development of various tissues and how de-regulation of these factors can cause, or is linked to, various human diseases

1. Molecular and Cellular Regulation of Skeletal Mygenesis 2. Proneural bHLH Genes in Development and Disease 3. The Hand2 Gene Dosage Effect in Developmental Defects and Human Congenital Disorders 4. E Proteins in Lymphocyte Development and Lymphoid Diseases 5. Id Proteins: Small Molecules, Mighty Regulators 6. E(spl): Genetic, Developmental and Evolutionary Aspects of a Group of Invertebrate Hes Proteins with Close Ties to Notch Signaling 7. Expression Dynamics and Functions of Hes Factors in Development and Diseases 8. Hey bHLH Transcription Factors 9. Stra13 and Sharp-1, the Non-Grouchy Regulators of Development and Disease 10. DEC1/STRA13/SHARP2 and DEC2/SHARP1 Coordinate Physiological Processes, Including Circadian Rhythms in Response to Environmental Stimuli