Advanced Topics in Forensic DNA Typing: Interpretation

Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions.

Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidenceWorked mixture examples illustrate the impact of different statistical approaches for reporting resultsIncludes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011

Section 1: DATA INTERPRETATION
Chapter 1: Data Interpretation Overview
Chapter 2: Data, Models, & Thresholds
Chapter 3: STR Alleles & Artifacts
Chapter 4: STR Genotypes
Chapter 5: STR Profiles 
Chapter 6: DNA Mixtures
Chapter 7: Low-Level DNA & Complex Mixtures
Chapter 8: Troubleshooting Data Collection

Section 2: STATISTICAL INTERPRETATION
Chapter 9: Statistical Interpretation Overview
Chapter 10: STR Population Data Analysis
Chapter 11: DNA Profile Frequency Estimates 
Chapter 12: DNA Mixture Statistics
Chapter 13: Coping with Missing Alleles
Chapter 14: Relationship Testing: Kinship Statistics
Chapter 15: Lineage Marker Statistics
Chapter 16: Laboratory Reports: Communicating Results and Conclusions

APPENDICES
Appendix 1: STR Allele Frequencies from U.S. Population Data 
Appendix 2: NRC I and NRC II Recommendations
Appendix 3: DAB Recommendations on Statistics
Appendix 4: Worked Mixture Example (by Dr. Michael D. Coble)