Polyphenols in Human Health and Disease

Polyphenols in Human Health and Disease documents antioxidant actions of polyphenols in protection of cells and cell organelles, critical for understanding their health-promoting actions to help the dietary supplement industry. The book begins by describing the fundamentals of absorption, metabolism and bioavailability of polyphenols, as well as the effect of microbes on polyphenol structure and function and toxicity. It then examines the role of polyphenols in the treatment of chronic disease, including vascular and cardiac health, obesity and diabetes therapy, cancer treatment and prevention, and more.

Explores neuronal protection by polyphenol metabolites and their application to medical careDefines modulation of enzyme actions to help researchers see and study polyphenols’ mechanisms of action, leading to clinical applicationsIncludes insights on polyphenols in brain and neurological functions to apply them to the wide range of aging diseases

Part I: Biomodification of polyphenols and mechanisms of action Overview of polyphenols and health research Absorption, metabolism and bioavailability of polyphenols Effect of microbes on polyphenol structure and function Polyphenol actions as enzyme modulators in health Oxidation and antioxidant activity of polyphenols Toxicities and identification of polyphenols

Part II: Polyphenols in prevention and treatment of chronic disease Polyphenols and vascular health Cardiac health and polyphenols Polyphenols in therapy of obesity and diabetes Polyphenols in brain and neurobiology health Cancer prevention and treatment by polyphenols Inflammation and immune functions Diverse diseases and physiological states modified by polyphenols