Protein Phosphorylation in Health and Disease

This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields.

Contributions from leading authoritiesInforms and updates on all the latest developments in the field

1. Wip1 -dependent signaling pathways in health and diseases Yun-hua Zhu and Dmitry V. Bulavin
2. HijAkt: The PI3k/Akt pathway in virus replication and pathogenesis Ewan F. Dunn and John H. Connor
3. Phosphoproteins in stress-induced disease Lucy E. Dalton, Eleanor Healey, James Irving & Stefan J. Marciniak
4. G-substrate: The Cerebellum and Beyond Shogo Endo
5. Targeting Phosphorylation of Eukaryotic Initiation Factor-2a to Treat Human Disease Melissa J. Fullwood, Wei Zhou and Shirish Shenolikar
6. Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia Jean-Antoine Girault
7. The Role of Protein Phosphorylation in Therapy-resistance and Disease Progression in Chronic Myelogenous Leukemia Wen Chun JUAN and S. Tiong ONG
8. Phosphatases driving mitosis: pushing the gas and lifting the brakes Erika Segear Johnson and Sally Kornbluth
9. Protein tyrosine phosphatases in cancer: Friends and Foes David P. Labbé, Serge Hardy, Michel L. Tremblay
10. Multiple Roles Of Stat3 In Cardiovascular Inflammatory Responses Cheh Peng Lim and Xin-Yuan Fu
11. PAKs in human disease Perry M. Chan and Ed Manser
12. Protein Phosphatases and Alzheimer’s Disease Steven P. Braithwaite, Jeffry B. Stock, Paul J. Lombroso, Angus C. Nairn
13. Role of the JNK pathway in human diseases Kanaga Sabapathy
14. Mass spectrometric tools for systematic analysis of protein phosphorylation Nicole St-Denis1 and Anne-Claude Gingras