Biomarkers of Neurological and Psychiatric Disease

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.

Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future researchChapters are extensively referenced to provide readers with a comprehensive list of resources on the topics coveredAll chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

1. General overview: biomarkers in neuroscience research - Michaela D. Filiou and Christoph W. Turck 2. Imaging brain microglial activation using positron emission tomography and translocator protein specific radioligands - David RJ Owen, Paul M Matthews 3. The utility of gene expression in blood cells for diagnosing neuropsychiatric disorders - Christopher H. Woelk, Akul Singhania, Josué Pérez-Santiago, Stephen J. Glatt, Ming T. Tsuang 4. Proteomic technologies for biomarker studies in psychiatry: advances and needs - Daniel Martins-de-Souza, Paul C. Guest, Natacha Vanattou-Saifoudine, Laura W. Harris, Sabine Bahn 5. Converging evidence of blood-based biomarkers for schizophrenia: an update - Man K.Chan, Paul C. Guest, Yishai Levin, Yagnesh Umrania, Emanuel Schwarz, Sabine Bahn, Hassan Rahmoune 6. Abnormalities in metabolism and hypothalamic-pituitary-adrenal axis function in schizophrenia - Paul C Guest, Daniel Martins-de-Souza, Natacha Vanattou-Saifoudine, Laura W Harris, Sabine Bahn 7. Immune and neuro-immune alterations in mood disorders and schizophrenia - Roosmarijn C Drexhage, Karin Weigelt, Nico van Beveren, Dan Cohen, Marjan A. Versnel, Willem A. Nolen Hemmo A. Drexhage 8. Behavioural and molecular biomarkers in translational animal models for neuropsychiatric disorders - Zoltán Sarnyai, Murtada Alsaif, Sabine Bahn, Agnes Ernst, Paul C. Guest, Eva Hradetzky, Wolfgang Kluge, Viktoria Stelzhammer and Hendrik Wesseling 9. Stem cell models for biomarker discovery in brain disease - Alan Mackay-Sim, George Mellick, Stephen Wood 10. The application of multiplexed assay systems for molecular diagnostics - Emanuel Schwarz, Nico JM VanBeveren, Paul C. Guest, Rauf Izmailov, Sabine Bahn 11. Algorithm development for diagnostic biomarker assays - Rauf Izmailov, Paul C. Guest, Sabine Bahn, Emanuel Schwarz 12. Challenges of introducing new biomarker products for neuropsychiatric disorders into the market - Sabine Bahn, Richard Noll, Anthony Barnes, Emanuel Schwarz, Paul C Guest 13. Towards personalized medicine in the neuropsychiatric field - Erik H.F. Wong, Jayne C. Fox, Mandy Y.M. Ng, Chi-Ming Lee 14. Clinical utility of serum biomarkers for major psychiatric disorders - Nico JM van Beveren and Witte JG Hoogendijk 15. The future: biomarkers, biosensors, neuroinformatics and e-neuropsychiatry - Christopher R Lowe