The Brain as a Drug Target

The brain is protected by the blood-brain barrier and this barrier prevents many drugs from entering the brain. This volume discusses various drug delivery and targeting strategies that are being developed to enhance the transport and distribution of drugs into the brain.

* Discusses new discoveries, approaches, and ideas * Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

1. Monoamine Transporters: Vulnerable and Vital Doorkeepers Zhicheng Lin, Juan J. Canales, Thröstur Björgvinsson, Morgane M. Thomsen, Hong Qu, Qing-Rong Liu, Gonzalo E. Torres, and S. Barak Caine 2. Therapeutic Targets in Alzheimer Disease and Related Tauopathies Christopher P. Corbo and Alejandra del C. Alonso 3. Therapeutic Targets for Neuroprotection and/or Enhancement of Functional Recovery Following Traumatic Brain Injury Matthew L. Kelso and James R. Pauly 4. Insulin, Synaptic Function, and Opportunities for Neuroprotection John G. Mielke and Yu-Tian Wang 5. Molecular Alterations in Glioblastoma: Potential Targets for Immunotherapy Azizul Haque, Naren L. Banik, and Swapan K. Ray 6. Molecular Signaling and Translational Significance of the Corticotropin Releasing Factor System Patrick J. Ronan, and Cliff H. Summers 7. Molecular targets of alcohol action: translational research for pharmacotherapy development and screening Giorgio Gorini, Richard L. Bell, and R. Dayne Mayfield 8. Brain Nicotinic Receptors as Emerging Targets for Drug Addiction: Neurobiology to Translational Research Shafiqur Rahman 9. Glutamatergic Neuroplasticity in Cocaine Addiction Joachim D. Uys and Kathryn J. Reissner 10. Role of the serotonergic system in alcohol dependence: from animal models to clinics Verity R. Johnson, Jason M. Weedman, Youssef Sari