Protein Prenylation, Part A

This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins.

Contributions from leading authoritiesInforms and updates on all the latest developments in the field

Chapter 1: Protein prenylation: A perspective on initial discoveries

John Glomset

Chapter 2: Insights into the function of prenylation from nuclear lamin farnesylation

Michael Sinensky

Chapter 3: Posttranslational Processing of Nuclear Lamins

Brandon S. J. Davies, Catherine Coffinier, Shao H. Yang, Hea-Jin Jung, Loren G. Fong, and Stephen G. Young

Chapter 4: Prenylated Proteins in Peroxisome Biogenesis

Robert Rucktäschel, Rezeda Mirgalieva, Ralf Erdmann

Chapter 5: Lipid Modification of Ras Superfamily GTPases: Not Just Membrane Glue

Emily J. Chenette,^, Channing J. Der

Chapter 6: Heterogeneous Prenyl Processing of the Heterotrimeric G protein Gamma Subunits

John Hildebrandt

Chapter 7: Farnesylation versus geranylgeranylation in G-protein-mediated light signaling

Masahiro Okada , Hidetoshi Kassai, Yoshitaka Fukada

Chapter 8: Organization and function of the Rab prenylation and recycling machinery

Kirill Alexandrov, Yaowen Wu, Wulf Blankenfeldt, Herbert Waldmann, Roger S. Goody

Chapter 9: Protein prenylation and CaaX processing in plants

Shaul Yalovsky

Chapter 10: Posttranslational isoprenylation on tryptophan residue in Bacillus subtilis

Masahiro Okada, Fumitada Tsuji, Youji Sakagami

Chapter 11: Global analysis of prenylated proteins by the use of a tagging via substrate approach

Lai N. Chan, Fuyuhiko Tamanoi

Chapter 12: Global Identification of Protein Prenyltransferase Substrates: Defining the Prenylated Proteome

Corissa L. Lamphear, Elaina A. Zverina, James L. Hougland, Carol A. Fierke

Chapter 13: Structural biochemistry of CaaX protein prenyltransferases

Michael A. Hast , Lorena S. Beese

Chapter 14: Genetic Analyses of the CAAX Protein Prenyltransferases in Mice

MOHAMED X. IBRAHIM, OMAR M. KHAN, MARTIN O. BERGO

Chapter 15: Farnesyl Transferase Inhibitors: From Targeted Cancer Therapeutic to a Potential Treatment for Progeria

W. Robert Bishop, Ronald Doll, Paul Kirschmeier