Membrane Proteins as Drug Targets

Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to new and improved pharmaceutical treatments for a wide range of illnesses such as heart disease, cystic fibrosis and depression.

Membrane Proteins as Drug Targets reviews the latest developments in the field.

Discusses new discoveries, approaches, and ideas in the field of membrane proteins and reviews how they are being used to develop new drugsContributions from leading scholars and industry expertsReference guide for researchers involved in molecular biology and related fields

1. Inverse Agonism at Serotonin and Cannabinoid Receptors

         Vincent J. Aloyo, Kelly A. Berg, William P. Clarke, Umberto Spampinato, and John A. Harvey

2.    G protein-coupled receptor heteromers as new targets for drug development

Sergi Ferré, Gemma Navarro, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carme Lluís and Rafael Franco

3.    Receptor activity modifying proteins and their potential as drug targets

Denise L. Wootten, John Simms, Debbie L. Hay, Arthur Christopoulos and Patrick M. Sexto

4.  Regulators of G Protein Signaling Proteins As Targets For Drug Discovery

Benita Sjögren, Levi L. Blazer and Richard R. Neubig

5.    Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets

Dumaine Williams and Lakshmi A. Dev

6.    The T1r2/T1r3 Sweet Receptor and Trpm5 Ion Channel: Taste Targets With Therapeutic Potential

Dennis Sprous and R. Kyle Palmer

7.     Membrane-associated enzymatic synthesis

Edward A. Esposito and Robert Weis