Fundamentals of Forensic DNA Typing

Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation.
This book reviews the methods of forensic DNA testing used in the first two decades since early 1980’s, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives.
Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable.

Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialectContinues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughoutAncillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Foreword Introduction Acknowledgments About the author

Chapter 1 Overview and History of DNA Typing Chapter 2 Basics of DNA Biology and Genetics Chapter 3 Historical Methods Chapter 4 Sample Collection, Storage and Characterization Chapter 5 DNA Extraction Chapter 6 DNA Quantitation Chapter 7 DNA Amplification (The Polymerase Chain Reaction) Chapter 8 Short Tandem Repeat Markers Chapter 9 Fundamentals of DNA separation and Detection Chapter 10 STR Genotyping and Data Interpretation Chapter 11 Statistical Interpretation: Evaluating the Strength of Forensic DNA Evidence Chapter 12 DNA databases Chapter 13 Quality Assurance Chapter 14 Forensic Challenges: Degraded DNA, Mixtures, and LCN Chapter 15 Additional Loci and Non-Human DNA Testing Chapter 16 Lineage Markers: Y Chromosome and mtDNA Testing Chapter 17 Applications of DNA Typing Chapter 18 Future Trends Appendix 1 Glossary of Terms Appendix 2 Useful Websites Appendix 3 Probability and Statistics