Translational Control in Health and Disease

Progress in Molecular Biology and Translational Science provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology and translational science. It contains contributions from leaders in their fields and abundant references. This volume focuses on translational control in health and disease.

* Contributions from leading scholars and industry experts * Reference guide for researchers involved in molecular biology and related fields

Chapter 1. The Molecular Basis of Translational Control

Chris S. Fraser

Chapter 2. Cell Signaling Pathways Affecting Protein Synthesis

John Blenis and Sarah Mahoney

Chapter 3. Effects of cell stress on protein synthesis and granule formation.

Nancy L. Kedersha and Paul Anderson

Chapter 4. miRNA-mediated gene silencing

Peter Sarnow

Chapter 5. The Role of Protein Synthesis in Cancer

Robert J. Schneider

Chapter 6. Localized Protein Synthesis and Synaptic Plasticity

Joel Richter, Mauro Costa-Mattioli and Nahum Sonenberg

Chapter 7. Translational Control During Early Development

Paul Lasko

Chapter 8. Ribosomal Protein S6 Kinase: From TOP mRNAs to Cell Size

Oded Meyhuhas

Chapter 9. Viruses

Anne Willis, Lisa Roberts and Richard Jackson(?)

Chapter 10. RNA Aptamers to Translational Components

Yoshikazu Nakamura

Chapter 11. Nonsense Mediated Decay and Regulation at Termination

Stuart Peltz