Advanced Topics in Forensic DNA Typing: Methodology

Intended as a companion to the Fundamentals of Forensic DNA Typing volume published in 2009, Advanced Topics in Forensic DNA Typing: Methodology contains 18 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field and citation to more than 2800 articles and internet resources. The book builds upon the previous two editions of John Butler’s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience.  This book provides the most detailed information written to-date on DNA databases, low-level DNA, validation, and numerous other topics including a new chapter on legal aspects of DNA testing to prepare scientists for expert witness testimony. Over half of the content is new compared to previous editions. A forthcoming companion volume will cover interpretation issues.

Contains the latest information - hot-topics and new technologiesWell edited, attractively laid out, and makes productive use of its four-color formatAuthor John Butler is ranked as the number one "high-impact author in legal medicine and forensic science, 2001 to 2011" by ScienceWatch.com

1.   Sample Collection, Storage, and Characterization
2.   DNA Extraction Methods
3.   DNA Quantitation
4.   PCR Amplification: Capabilities and Cautions
5.   Short Tandem Repeat (STR) Loci and Kits
6.   Capillary Electrophoresis: Principles and Instrumentation
7.   Quality Assurance and Validation
8.   DNA Databases: Uses and Issues
9.   Missing Persons and Disaster Victim Identification Efforts
10.  Degraded DNA
11.  Low-Level DNA Testing: Issues, Concerns, and Solutions
12.  Single Nucleotide Polymorphisms and Applications
13.  Y-Chromosome DNA Testing
14.  Mitochondrial DNA Analysis
15.  X-Chromosome Analysis
16.  Non-Human DNA
17.  New Technologies and Automation
18.  Legal Aspects of DNA Testing and the Scientific Expert in Court
Appendix 1  Reported Sizes and Sequences of STR Alleles
Appendix 2  Familial DNA Searches: Potential, Pitfalls, and Privacy Concerns
Appendix 3  List of Suppliers for DNA Instruments, Reagents, Services
Appendix 4  Interviews Supporting Legal Aspects of DNA Testing