Folic Acid and Folates

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.

*Includes color illustrations
*Available on ScienceDirect
*Longest running series published by Academic Press
*Contributions by leading international authorities

1. Folate-Mediated One-Carbon Metabolism
Jennifer T. Fox and Patrick J. Stover

2. Mathematical Models of Folate-Mediated One-Carbon Metabolism
H. Frederik Nijhout, Michael C. Reed and C.M. Ulrich

3. Folate Deprivation, the Methionine Cycle and Alzheimer¡¦s Disease
Flaubert Tchantchou and Thomas B. Shea

4. Benefits and Risks of Folic Acid Supplementation
Young-In Kim

5. Molecular Mechanisms of Adaptation to Folate Deficiency
Ilan Ifergan and Yehuda G. Assaraf

6. Structure and Function of the Reduced Folate Carrier: A Paradigm of a Major Facilitator Superfamily Mammalian Nutrient Transporter
Larry H. Matherly and Zhanjun Hou

7. Renal Conservation of Folates: Role of Folate Transport Proteins
Vijaya L. Damaraju, Carol E. Cass and Michael B. Sawyer

8. Exploitation of the Folate Receptor in the Management of Cancer and Inflammatory Disease
Christopher P. Leamon and Ann L. Jackman

9. Folate Receptor Expression in Pituitary Adenomas: Cellular and Molecular Analysis
Chheng-Orn Evans, Congjun Yao, David Leborde and Nelson M. Oyesiku

10. Regulation of Human Dihydrofolate Reductase Activity and Expression
Emine Ercikan Abali, Nancy E. Skacel, Hilal Celikkaya, Yi-Ching Hsieh

11. Catalysis of Methyl Group Transfers Involving Tetrahydrofolate and B12
Stephen W. Ragsdale

12. Methyltetrahydrofolate in Folate-Binding Protein Glycine N-Methyltransferase
Zigmund Luka

13. Mechanism-Based Inhibitors of Folylpoly-ƒ×-glutamate Synthetase and ƒ×-Glutamyl Hydrolase: Control of Folylpoly-ƒ×-glutamate Homeostasis as a Drug Target
James K. Coward and John J. McGuire

14. Methylenetetrahydrofolate Reductase, Common Polymorphisms and Relation to Disease
Philip Thomas and Michael Fenech

15. Mitochondrial Methylenetetrahydrofolate Dehydrogenase, Methenyltetrahydrofolate Cyclohydrolase and Formyltetrahydrofolate Synthetases
Karen E. Christensen and Robert E. MacKenzie

16. The Structure and Mechanism of 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase
Jeremy P. Derrick