Asthma and COPD: Basic Mechanisms and Clinical Management

The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.

Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical managementPresents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPDMost extensive reference to primary literature on both Asthma and COPD in one source.Easy-to-read summaries of the latest advances alongside clear illustrations

1. Definitions, Epidemiology and Genetics of Asthma and COPD
2. Epidemiology
3. Natural History
4. Genetics of Asthma and COPD
5. Pulmonary Physiology
6. Airway Pathology
7. Airway Remodeling
8. Animal Models
9. Mast Cells and Basophils
10. Dentritic Cells
11. Macrophages
12. Eosinophils
13. Lymphocytes
14. Neutrophils
15. Fibroblasts
16. Epithelial Cells
17. Mucus and Mucin-Secreting Cells
18. Airway Smooth Muscle
19. Tracheobronchial Circulation
20. Pulmonary Vessels
21. Adhesion Molecules
22. Extracellular Matrix
23. Prostanoids
24. Leukotrienes and Lipoxins
25. Reactive Oxygen Species
26. Chemokines
27. Cytokines
28. Matrix Degrading Proteinases
29. Growth Factors,
30. Nitric Oxide
31. Transcription Factors
32. Neural and Humoral Control
33. Pathophysiology of Asthma
34. Pathogenesis of COPD
35. Allergens
36. Occupational Agents
37. Infections
38. Exercise as a Stimulus
39. Atmospheric Pollutants
40. Drugs
41. Diagnosis
42. Non-invasive Assessment of Airway Inflammation
43. Imaging
44. Systemic Manifestations
45. Cardiovascular Effects
46. Allergen Avoidance
47. Smoking Cessation
48. â2-adrenoceptor Agonists
49. Anticholinergic Bronchodilators
50. Theophylline
51. Corticosteroids
52. Mediator Antagonists
53. Antibiotics
54. Long-term Oxygen Therapy
55. Immunomodulators
56. Pulmonary Vasodilators
57. Ventilator Support
58. Pulmonary Rehabilitation
59. Surgery and Other Mechanical Interventions
60. Other Therapies
61. Future Therapies
62. Health Economics
63. Management of Chronic Asthma in Adults
64. Asthma Exacerbations
65. Childhood Asthma
66. Treatment for Stable COPD
67. Acute Exacerbations of COPD
68. Education and Self-Management