Hormones and Signaling

Hormones and Signaling focuses on the mechanism of gene regulation at the cellular level. It also covers the way hormones act to modulate gene regulation and animal development.

Includes information on:

Nuclear receptors, coactivators, and corepressorsMembrane receptors, kinases, and phosphorylation on cascadesHormonal regulation of developmentCalcium channels and neurotransmittersChromatin, transcription factors, and regulation of gene expressionJAK/STAT pathwaysHormone-regulated development and gene "knock-out"

E.B. Thompson, Glucocorticoid and Oxysterol-induces Apoptosis of Lymphoid Cells.
A.M. Schmidt, J-L. Wautier, D.M. Stern, and S.D. Yun, RAGE: A Receptor with a Taste for Multiple Ligands and Varied Pathophysiologic States.
R.J. Lefkowitz and A.D. Macrae, The Function and Regulation of the G Protein-Coupled Receptor Kinases.
G. Kuiper, S. Nilsson, and J-A. Gustafsson, Characteristics and Function of the Novel Estrogen Receptor beta.
M.E. Lippman and C.Tang, EGF Family Receptors and Their Ligands in Human Cancer.
D.L. Garbers and T.A. Quill, Fertilization: Common Molecular Signaling Pathways Across the Species.
A. Minden and M. Karin, The JNK Family of MAP Kinases: Regulation and Function.
P. Devchand and W. Wahli, PPAR alpha: Tempting Fate with Fat.
S.R. Datta and M.E. Greenberg, Molecular Mechanisms of Neuronal Survival and Apoptosis.
D.J. Mangelsdorf and P.J. Willy, Nuclear Orphan Receptors: The Search for Novel Ligands and Signaling Pathways.