Protein Targeting, Transport, and Translocation

Protein Targeting, Transport, and Translocation presents an in-depth overview on the topic of protein synthesis, covering all areas of protein science, including protein targeting, secretion, folding, assembly, structure, localization, quality control, degradation, and antigen presentation. Chapters also include sections on the history of the field as well as summary panels for quick reference. Numerous color illustrations complement the presentation of material. This book is an essential reference for anyone in biochemistry and protein science, as well as an excellent textbook for advanced students in these and related fields.

Basic principles and techniquesTargeting adn sorting sequencesProtein export in bacteriaMembrane protein integration into ER and bacterial membranesProtein translocation across the ERDisulfide bond formation in prokaryotes and eukaryotesQuality control in the export pathwayImport of proteins into organellesThe secretory pathwayVesicular transportSpectacular color throughout

Methods in Protein Targeting, Translocation and Transport
Targeting Sequences
Protein Export in Bacteria
Protein Sorting at the Membrane of the Endoplasmic Reticulum
Membrane Protein Insertion into Bacteial Membranes and Endoplasmic Reticulum
Disulfide Bond Formation in Prokaryotes and Eukaryotes
The Unfolded Protein Response
Protein Quality Control in the Export Pathway: The Endoplasmic Reticulum and its Cytoplasmic Proteasome Connection
Translocation of Proteins into Mitochondria
The Import and Sorting of Protein into Chloroplasts
Import of Proteins into Peroxisomes
Nucleocytoplasmic Transport
Protein Transport to the Yeast Vacuole
The Secretory Pathway
Vesicular Transport
Conclusion/Perspective