Mechanosensitive Ion Channels, Part B

Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include ENaC Proteins in Vascular Smooth Muscle Mechanotransduction; Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids; MechanoTRPs and TRPA1; TRPC; The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism. Lessons From Polycystin-2 (TRPP2); Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels; Hair Cell Mechanotransduction: The Dynamic Interplay between Structure and Function; Pharmacology of Hair Cell MS Channels; Hair Cell Mechanotransduction; Models of Hair Cell Mechanotrasduction; Touch; Mechanosensitive Ion Channels in Dystrophic Muscle; Mechanotransduction in Endothelial Cells;
MS Channels in Tumor Cell Migration; Mechanosensitive Channels in Regulating Smooth Muscle Contraction in the GI; Mechanosensitive Ion Channels in Blood-Pressure-Sensing Baroreceptor Neurons.

Chapter 1: Mechanosensitive Ion Channels of Spiders: Mechanical Coupling, Electrophysiology, and Synaptic Modulation

Chapter 2: Ion Channels for Mechanotransduction in the Crayfish Stretch Receptor

Chapter 3: Mechanosensitive Ion Channels in Caenorhabditis elegans

Chapter 4: Properties and Mechanism of the Mechanosensitive Ion Channel Inhibitor GsMTx4, a Therapeutic Peptide Derived from Tarantula Venom

Chapter 5: Mechanosensitive Channels in Neurite Outgrowth

Chapter 6: ENaC Proteins in Vascular Smooth Muscle Mechanotransduction

Chapter 7: Regulation of the Mechano‐Gated K_2P Channel TREK‐1 by Membrane Phospholipids

Chapter 8: MechanoTRPs and TRPA1

Chapter 9: TRPCs as MS Channels

Chapter 10: The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism: Lessons from Polycystin‐2 (TRPP2)

Chapter 11: Lipid Stress at Play: Mechanosensitivity of Voltage-Gated Channels

Chapter 12: Hair Cell Mechanotransduction: The Dynamic Interplay Between Structure and Function

Chapter 13: Insights into the Pore of the Hair Cell Transducer Channel from Experiments with Permeant Blockers

Chapter 14: Models of Hair Cell Mechanotransduction

Chapter 15: Touch

Chapter 16: Mechanosensitive Ion Channels in Dystrophic Muscle

Chapter 17: MscCa Regulation of Tumor Cell Migration and Metastasis

Chapter 18: Stretch‐Activated Conductances in Smooth Muscles

Chapter 19: Mechanosensitive Ion Channels in Blood Pressure‐Sensing Baroreceptor Neurons

Index