Rinderpest and Peste des Petits Ruminants: Virus Plagues of Large and Small Ruminants

Rinderpest and Peste des Petits Ruminants tells the story of how, by the year 2010, scientists are set to globally eradicate one of the great historic plagues that has ravaged human livestock for centuries. Descriptions of the disease in Europe date back to the 4th century and it was regularly re-introduced following wars and other civil unrest until late in the 19th century. It was introduced with devastating effect into Africa towards the end of the 19th century and is now widespread across sub-Saharan Africa, the Middle East and Southern Asia. Its causative agent, rinderpest virus, a morbillivirus very closely related to human measles virus, decimates the cattle population along with those of other susceptible domestic ruminants and many wildlife species wherever it is present.

The history of Rinderpest including the history of vaccines and vaccinationDetails other MorbillavirusesEpidemiology and transmission of Rinderpest

Preface
General Introduction
Rinderpest, An Old Worldwide Story
Rinderpest in Africa
The Morbilliviruses
Rinderpest and Peste des Petits Ruminants Viruses
The Disease
Epidemiology and Transmission of Rinderpest
Rinderpest and Wildlife, A Controversy
Immunology of Rinderpest: An Immunosuppression but a Lifelong Protection
Old Prophylactic Methods
History of Vaccines and Vaccination
New Generation Vaccines Against Rinderpest and Peste des Petits Ruminants
Towards Eradication of Rinderpest
Conclusions
Glossary
Index
Index of the Key Players in the History of Rinderpest Research
Key References List