Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications

Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications provides comprehensive knowledge of the preparation, modification and applications of protein and peptide nanofibers. The book reviews the synthesis and strategies necessary to create protein and peptide nanofibers, such as self-assembly (including supramolecular assembly), electrospinning, template synthesis, and enzymatic synthesis. Then, the key chemical modification and molecular design methods are highlighted that can be utilized to improve the bio-functions of these synthetic fibers. Finally, fabrication methods for key applications, such as sensing, drug delivery, imaging, tissue engineering and electronic devices are reviewed.

This book will be an ideal resource for those working in materials science, polymer science, chemical engineering, nanotechnology and biomedicine.

Reviews key chemical modification and molecular design methods to improve the bio-functions of synthetic peptide and protein nanofibersDiscusses the most important synthesis strategies, including supramolecular assembly, electrospinning, template synthesis and enzymatic synthesisProvides information on fabrication of nanofibers for key applications such as sensing, imaging, drug delivery and tissue engineering

 Section A Fabrication and characterizations of artificial  protein and peptide nanofibers

 1 Supramolecular self-assembly: A facile way to fabricate protein  and peptide nanomaterials  Luyang Zhao, Xuehai Yan

 2 Self-assembly formation of peptide and protein nanofibers on  surfaces and at interfaces Shuwei Sun, Zhiqiang Su, Gang Wei

 3 Fabrication of amyloid nanofiber matrices by electrospinning Devina Jaiswal, Sara Katebifar, Swetha Rudraiah,  Sangamesh G. Kumbar

 4 Novel protein and peptide nanofibrous structures  via supramolecular co-assembly Christian Helbing, Klaus D. Jandt

 5 Characterization techniques of protein and peptide nanofibers:  Self-assembly kinetics  Gang Wei

Section B Enhanced functions of nanofibers by sequence  design and modification

 6 Protein synthesis and characterization  Shobhit Kadakeri, Michael R. Arul, Rosalie Bordett,  Nithyadevi Duraisamy, Hemantkumar Naik, Swetha Rudraiah

 7 Design of functional peptide nanofibers based on amyloid motifs Wenfeng Wei, Zhiqiang Su

 8 Design of amphiphilic peptide nanofibers Mustafa O. Guler

 9 Nanofiber matrices of protein mimetic bioactive peptides  for biomedical applications Allen Zennifer, Muthu Parkkavi Sekar, Anuradha Subramanian, Swaminathan Sethuraman

 10 Synergetic integration of computer-aided design,  experimental synthesis, and self-assembly for the rational  design of peptide/protein nanofibrils Ke Zheng, Jing Ren, Yawen Liu, Shengjie Ling

 11 Composite nanofiber matrices for biomedical applications  Ramya Dhandapani, Amrutha Manigandan, Swaminathan Sethuraman, Anuradha Subramanian

 12 Nanofiber-based hydrogels and aerogels  Li Sun, Aiguo Wu 

Section C Related applications of artificial protein  and peptide nanofibers

13 Protein and peptide nanostructures for drug and gene delivery  Uma Maheswari Krishnan

14 Protein and peptide nanofiber matrices for the regenerative  medicine Seyed Mohammad Mir, Aneela Anwar, Ibrahim Dulijan,  Alok Kumar, Xiaojun Yu

15 Fibrous scaffolds for bone tissue engineering  Jennifer Moy, Apurva Limaye, Treena Livingston Arinzeh

16 Assembled peptides for biomimetic catalysis Mengfan Wang, Wei Qi

17 New protein-based smart materials  Lei Wang, Xin Huang

18 Nanofibers for soft-tissue engineering  Sama Abdulmalik, Sara Katebifar, Jonathan Nip, Laurie Yousman,  Paulina Szarejko, Jiana Baker, Swetha Rudraiah,  Sangamesh G. Kumbar