Comprehensive Natural Products III

Comprehensive Natural Products III, Third Edition, updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community.

Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the fieldBridges the gap in knowledge by covering developments in the field since the second edition published in 2010Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easilyEnsures that the knowledge within is easily understood by and applicable to a large audience

1. Structural Diversity of Natural Products and Secondary Metabolites a. Major natural products families and biosynthesis

2. Structural Diversity of Natural Products and Secondary Metabolites b. Terrestrial, marine, and prokaryotic sources of natural products and chemical biology (Producing organisms, structural analyses, and biosynthetic pathways. To be split across two volumes for a comprehensive review covering all recent discoveries and advances.)

3. Amino Acids, Peptides and Proteins

4. Carbohydrates, Nucleosides and Nucleic Acids

5. Enzymes and Enzyme Mechanisms (Radical SAM enzymes, metalloenzymes, Lewis acid/base versus radical-mediated mechanisms, etc.)

6. Development and Modification of Biological Molecules and Pathways (Synthetic biology, systems biology, biological pathway engineering, protein engineering, etc.)

7. Modern Methods for the Study of Natural Products and Their Biosynthesis (Analytical, chemical and genetic methods and new bioinformatics tools)

8. Index