Biointegration of Medical Implant Materials

Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia.

Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integrationDiscusses soft tissue biointegration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstructionIncludes new information on a variety of tissue regeneration techniques and applications

1. Biointegration: an introduction

Part One Soft tissue biointegration 2. Interface biology of stem cell-driven tissue engineering: concepts, concerns, and approaches 3. Replacement materials for facial reconstruction at the soft tissue–bone interface 4. Tissue engineering for small-diameter vascular grafts 5. Clinical applications of mesenchymal stem cells

Part Two Tissue regeneration 6. Cardiac Regeneration 7. Tissue-based products 8. Tendon and tissue regeneration 9. Integration of dental implants: molecular interplay at tissue-material interface 10. Biointegration of bone graft substiutes from osteointegration to osteotranduction 11. Stem cell-based therapeutic approaches toward corneal regeneration

Part Three Drug delivery 12. Biocompatibility of materials and its relevance to drug delivery and tissue engineering 13. Inorganic nanoparticles for targeted drug delivery 14. Applications of alginate biopolymer in drug delivery

Part Four Design considerations 15. Failure mechanisms of medical implants and their effects on outcomes 16. Biointegration of three-dimensional-printed biomaterials and biomedical devices