Octacalcium Phosphate Biomaterials: Understanding of Bioactive Properties and Application

Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry.

OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material.

Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties Presents the clinical potential of octacalcium phosphate biomaterialsProvides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration

1. Octacalcium Phosphate Biomaterials – Past present and Future 2. Octacalcium phosphate effects on the systematic and local factors that regulate bone cell activity 3. Octacalcium phosphate and the Biomineralisation of bone, cellular interactions and their role in bone repair 4. Octacalcium Phosphate bone replacement and drug delivery 5. Dissolution and growth of Octacalcium Phosphate in the presence of tooth proteins 6. The influence of sterilization on Octacalcium phosphate for clinical applications 7. An osteoinductive biomaterial Octacalcium Phosphate and its mechanism for bone formation 8. Novel scaffold composites containing Octacalcium Phosphate and their role in bone repair 9. Synthesis methodologies options for large scale manufacture of Octacalcium Phosphate 10. Biomimetic synthesis of calcium phosphate-based biomaterials for hard tissue regeneration 11. Future analysis techniques to assess mechanical and physiological behavior of novel calcium phosphate materials including Octacalcium Phosphate – In-vivo human clinical model 12. Octacalcium phosphate for implant coating 13. Calcium phosphate-based bone graft substitutes and the special roles of Octacalcium phosphate materials 14. Unique compositional and structural properties of OCP among calcium phosphate 15. Octacalcium phosphate collagen composites and their clinical application