Management of Periprosthetic Joint Infections (PJIs)

Management of Periprosthetic Joint Infections (PJIs): Management of PJIs discusses periprosthetic joint infection (PJI), a fairly rare occurrence that is nonetheless one of the most serious complications in joint replacement surgery. Intricate interactions between the pathogen, the host, and the implant can result in PJIs which are not only physically devastating for the patient, but also financially crippling for health authorities and insurance companies.

Actions taken to minimize the risk of PJIs can be extremely challenging for the orthopaedic community. Consequently, new research, which is detailed in this comprehensive book, is being undertaken to minimize and manage these challenging infections.

Provides essential background knowledge on the mechanisms and identification of PJIsDedicated chapters focus on the complex, but vital eccentricities between PJIs in different areas of the bodyContains contributions from a mixture of clinical and academic experts in the field, thus ensuring balanced coverage

Part One: Fundamentals of periprosthetic joint infections

1: Prevention of joint infections

2: Biofilm formation and the biological response

3: Biomaterials in treatment of orthopedic infections

4: S53P4 bioactive glass

5: Experimental models in orthopedic infection research

Part Two: Types of periprosthetic joint infections

6: Periprosthetic infection in the hip joint

7: Infection in total knee arthroplasty

8: Periprosthetic infection in shoulder and elbow joints

Part Three: Managing and treating periprosthetic joint infections

9: Practice and guidelines for treating periprosthetic joint infections: Single- and two-stage revision

10: PMMA beads and spacers for local antibiotic administration

11: Pathogen-directed antibiotic therapy

Part Four: Case studies

12: Imaging of prosthetic joint infections