Extracellular Matrix-derived Implants in Clinical Medicine

Extracellular Matrix-Derived Implants in Clinical Medicine comprehensively covers the emergence of tissue engineering and regenerative medicine over the past few decades, along with discussions of continuous funding and research.

The book provides a state-of-the-art review of this increasingly important technology and how it is translating from bench to bedside. Part One of the book looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological, while Part Two examines the challenges in harvesting, processing, and manufacturing of extracellular matrices, with a final section reviewing the international regulatory environment and economics of tissue-based products.

Addresses issues of tissue engineering and regenerative medicine from a biomaterials industry perspectiveLooks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurologicalExamines the challenges in harvesting, processing, and manufacturing of extracellular matricesReviews the international regulatory environment and economics of tissue-based products

1 Introduction

Part 1 Historical use of human and animal tissues in medical applications

2 Past and present ECM-based vascular biomaterials

3 Next generation ECM-based vascular biomaterials

4 Extra-cellular matrix derived tissues for soft tissue repair

5 Extra-cellular matrix derived tissues for hard tissue repair

6 Extra-cellular matrix derived tissues for neurological applications

Part 2 Sourcing, processing and manufacturing extracellular matrices

7 Sourcing animal and human tissue for implant use

8 Challenges in ECM product development: processing and regulatory

9 Human placental tissue-derived materials (amnion and/or chorion)