Inorganic Controlled Release Technology: Materials and Concepts for Advanced Drug Formulation

Inorganic Controlled Release Technology: Materials and Concepts for Advanced Drug Formulation provides a practical guide to the use and applications of inorganic controlled release technology (iCRT) for drug delivery and other healthcare applications, focusing on newly developed inorganic materials such as bioresorbable glasses and bioceramics. The use of these materials is introduced for a wide range of applications that cover inorganic drug delivery systems for new drug development and the reformulation of existing drugs. The book describes basic concepts, principles, and industrial practices by discussing materials chemistry, physics, nano/microstructure, formulation, materials processing, and case studies, as well as the evaluation and characterization of iCRT systems commonly investigated during industrial R&D.

Provides the first book on inorganic controlled release technology (iCRT), covering key aspects from chemistry, physics, synthetic methods, formulation design, characterization and evaluationIncludes several industry-related case studies to provide practical guidance on how to use iCRT as an alternative to organic polymers systems for both future drug developments and other active ingredient applicationsDemonstrates how iCRT offers an unmet business need for improved, controlled release of actives versus traditional CRT systems, which are known to have difficulty with the controlled delivery of both poorly and highly water soluble drug compounds

Chapter 1. Materials for Inorganic Controlled Release Technology
Chapter 2. Fundamentals of Drug Controlled Release
Chapter 3. Characterization of Inorganic Controlled Release Technology
Chapter 4. Silica-based Amorphous Drug Delivery Systems
Chapter 5. Bioactive Glass-ceramic Controlled Release Systems
Chapter 6. Calcium Phosphate Materials for Controlled Release System
Chapter 7. Other Inorganic Controlled Release Technology
Chapter 8. Future development of iCRT