Strategies and Tactics in Organic Synthesis

A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, we are given stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done, and we are educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world.

Foreword,   Albert Eschenmoser       Preface,   Michael Harmata Total Synthesis of Strychnos Alkaloids,   Rodrigo B. Andrade Total Synthesis of Celogentin C: Development of an Unusual Indole-Imidazole Oxidative Coupling,   Steven L. Castle A Carbonyl-Enabled Synthesis of the Guaiane Sesquiterpene Englerin A,   William J. Chain Synthesis of the Sesquiterpenes Anislactone A and Merrilactone A,   Michael Greaney Symmetry-Driven Total Synthesis of Merrilactone A and Resolvin E2,   Masayuki Inoue Studies on bis - 1, 2, 4 - triazine ligands: Privileged Ligands for Separating Actinides from Lanthanides,   Frank Lewis, Laurence M. Harwood Synthesis of (+) Hamigeran B using an Intramolecular Alkynylogous Mukaiyama Aldol Reaction,   Michel Miesch Exploring Prins Strategies for the Synthesis of Okilactomycin,   Karl Scheidt Taking Risks in Complex Synthesis Design,  Erik J. Sorensen Stereoselective Addition of Halogen to Conjugated Enynes and Its Application in the Total Synthesis of (-)-Kumausallene,   Weiping Tang Total Synthesis of Aspergillide C,   Stephen P. Waters Index