Therapeutics of Parkinsons Disease and Other Movement Disorders

Over the past few decades, neurology has seen spectacular developments in diagnostic techniques, particularly in neuroimaging and molecular genetics, accompanied by an increasing number of effective therapies to treat neurological disease. This is particularly true for the field of movement disorders.  Since the highly successful introduction of levodopa about 40 years ago, the therapeutic options for Parkinson’s disease have grown exponentially, often making treatment decisions difficult. 
This is the only current book on movement disorders to emphasize treatment.  The authors, experts in their field, have used evidence from randomized controlled clinical trials to develop practical recommendations for every day clinical practice, bringing their personal clinical acumen and therapeutic wisdom to the book.Provides a comprehensive update on therapies for Parkinson’s disease and other movement disordersDescribes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non–motor symptoms, and surgical managementFeatures summary tables and algorithms that serve as a quick reference guide for practical treatment decisions  The expert guidance of recognised authorities will enable readers of this book to plan their patients’ care with greater confidence
Therapeutics of Parkinson′s Disease & Other Movement Disorders is essential reading for residents in clinical neurology, clinical research fellows in neurology and related disciplines, general neurologists, and movement disorder specialists, as well as those working in the pharmaceutical industry with an interest in movement disorders.


Spis treści:
Contents
Preface
Contributors
PART I PARKINSON’S DISEASE AND PARKINSONISM
1 The Etiopathogenesis of Parkinson’s Disease: Basic Mechanisms of Neurodegeneration
C . Warren Olanow and Kevin McNaught
2 Physiology of Parkinson’s Disease
Shlomo Elias, Zvi Israel and Hagai Bergman
3 Pharmacology of Parkinson’s Disease
Jonathan M. Brotchie
4 The Treatment of Early Parkinson’s Disease
Olivier Rascol and Regina Katzenschlager
5 Treatment of Motor Complications in Advanced Parkinson’s Disease
Susan H. Fox and Anthony E. Lang
6 Managing the Non–Motor Symptoms of Parkinson’s Disease
Werner Poewe and Klaus Seppi
7 Surgery for Parkinson’s Disease
Jens Volkmann
8 Future Cell– and Gene–Based Therapies for Parkinson’s Disease
Tomas Björklund, Asuka Morizane, Deniz Kirik and Patrik Brundin
9 Parkinson–Plus Disorders
Martin Köllensperger and Gregor K. Wenning
PART II TREMOR DISORDERS
10 Essential Tremor
Rodger J. Elble
11 Other Tremor Disorders
Günther Deuschl
PART III DYSTONIA, CRAMPS, AND SPASMS
12 Pathophysiology of Dystonia.
Mark Hallett
13 General Management Approach to Dystonia
Cynthia L. Comella
14 Botulinum Toxin for Treatment of Dystonia
Dirk Dressler
15 Surgical Treatments of Dystonia
Christopher Kenney and Joseph Jankovic
16 Wilson’s Disease
George J. Brewer
17 Cramps and Spasms
Christine D. Esper, Pratibha G. Aia, Leslie J. Cloud and Stewart A. Factor
18 Stiff Person Syndrome
Philip D. Thompson and Hans–Michael Meinck
PART IV CHOREA, TICS AND OTHER MOVEMENT DISORDERS
19 Huntington Disease
Kevin M. Biglan and Ira Shoulson
20 Chorea
Francisco Cardoso
21 Treatment of Tics and Tourette Syndrome
Harvey S. Singer and Erika L.F. Hedderick
22 Therapeutics of Paroxysmal Dyskinesias
Shyamal H. Mehta and Kapil D. Sethi
23 Treatment of Miscellaneous Disorders
Marie Vidailhet, Emmanuel Roze and David Grabli
24 Myoclonus
Shu–Ching Hu, Steven J. Frucht and Hiroshi Shibasaki
PART V DRUG–INDUCED MOVEMENT DISORDERS
25 Neuroleptic–Induced Movement Disorders
S. Elizabeth Zauber and Christopher G. Goetz
26 Other Drug–Induced Dyskinesias
Oscar S. Gershanik
PART VI ATAXIA AND DISORDERS OF GAIT AND BALANCE
27 Ataxia.
Thomas Klockgether
28 Treatment of Gait and Balance Disorders
Bastiaan R. Bloem, Alexander C. Geurts, S. Hassin–Baer and Nir Giladi
PART VII RESTLESS LEGS SYNDROME
29 The Restless Legs Syndrome
Richard P. Allen and Birgit Högl
PART VIII PEDIATRIC MOVEMENT DISORDERS
30 Pediatric Movement Disorders
Jonathan W. Mink
PART IX PSYCHOGENIC MOVEMENT DISORDERS
31 Psychogenic Movement Disorders
Elizabeth Peckham and Mark Hallett
Index


Okładka tylna:
Over the past few decades, neurology has seen spectacular developments in diagnostic techniques, particularly in neuroimaging and molecular genetics, accompanied by an increasing number of effective therapies to treat neurological disease. This is particularly true for the field of movement disorders.  Since the highly successful introduction of levodopa about 40 years ago, the therapeutic options for Parkinson’s disease have grown exponentially, often making treatment decisions difficult. 
This is the only current book on movement disorders to emphasize treatment.  The authors, experts in their field, have used evidence from randomized controlled clinical trials to develop practical recommendations for every day clinical practice, bringing their personal clinical acumen and therapeutic wisdom to the book.Provides a comprehensive update on therapies for Parkinson’ s disease and other movement disordersDescribes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non–motor symptoms, and surgical managementFeatures summary tables and algorithms that serve as a quick reference guide for practical treatment decisions  The expert guidance of recognised authorities will enable readers of this book to plan their patients’ care with greater confidence
Therapeutics of Parkinson′s Disease & Other Movement Disorders is essential reading for residents in clinical neurology, clinical research fellows in neurology and related disciplines, general neurologists, and movement disorder specialists, as well as those working in the pharmaceutical industry with an interest in movement disorders.